Excerpt from Syphilis: Its Diagnosis and Treatment
Probably no isolated disease has been the subject of so extensive and contradictory a literature as syphilis.
The prevalence of the malady, the distressing symptoms with which it is associated, and the lamentable results to which it may lead in its later stages, serve to explain the attention it has received from surgical writers.
A review of the literature of the subject reveals the circumstance that it is upon the question of the treatment of the disease that the most copious dissertations have been bestowed. There is hardly a drug known to medicine that has not, at some time or another, been advocated as effective in the management of this complaint.
At an early period one fact arose into prominence out of the chaotic mass of dicta with which the treatment of syphilis was confounded - the fact that mercury had a beneficial effect upon the disease. This conviction, carried into practice, led to some extravagance of action. There soon came to be recorded two periods of extremes in the use of the drug. At one period mercury was administered in amounts so large as to deliberately produce the phenomena of mercurial poisoning; at the other period the employment of the drug was condemned, not only on the ground that it was useless, but on the belief that it caused some of the grosser lesions with which the late stages of the complaint were associated.
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