Inhibition Of Cell Proliferation Through R.i.p. Of Creb3l1 Bray Denard

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Bray Denard - «Inhibition Of Cell Proliferation Through R.i.p. Of Creb3l1»

О книге

“Inhibition of Cell Proliferation through Regulated Intramembrane Proteolysis of CREB3L1” guides the reader though the discovery of CREB3L1 as a membrane-bound transcription factor that prevents the proliferation of virus-infected cells. Upon activation, CREB3L1 is found to block the proliferation of cells infected with diverse DNA and RNA viruses, including murine gamma-herpesvirus 68, HCV, West Nile virus, and Sendai virus. The reader is then lead through the discovery that doxorubicin, a widely used anti-cancer drug, requires CREB3L1 to perform the anti-proliferative function utilized in cancer therapy. Data is presented that doxorubicin stimulates de novo synthesis of ceramide, which in turn activates the regulated intramembrane proteolysis of CREB3L1. This leads to the transcription of anti-proliferative genes that block tumor cell proliferation. Это и многое другое вы найдете в книге Inhibition Of Cell Proliferation Through R.i.p. Of Creb3l1 (Bray Denard)

Полное название книги Bray Denard Inhibition Of Cell Proliferation Through R.i.p. Of Creb3l1
Автор Bray Denard
Ключевые слова медицина, фармакология, медико-биологические дисциплины
Категории Образование и наука, Для техникумов и вузов
ISBN 9783659230165
Издательство
Год 2012
Название транслитом inhibition-of-cell-proliferation-through-r-i-p-of-creb3l1-bray-denard
Название с ошибочной раскладкой inhibition of cell proliferation through r.i.p. of creb3l1 bray denard