Antiepileptic and antipsychotic activities of Oxalis corniculata Linn Gaurav Gupta, Firoz Anwar and Muhammad Afzal

Acute and chronic administration of Oxalis corniculata L. has anti-epileptic activity against MES and INH induced convulsions by reducing tonic hind limb extension phase and delaying onset of convulsion. It also observed that plant extract possess anti-psychotic activity against apomorphine induced stereotyped behavior and haloperidol induced catalepsy by reducing the stereotyped behavior as well as potentiated the cataleptic score. Anti-epileptic activity of Oxalis corniculata L. may be attributed to the involvement of either by blocking the Na+ channels or enhancing the GABAergic system in the neuronal of the brain. Furthermore, anti-psychotic activity of Oxalis corniculata may be due to involvement of dopaminergic pathway. The identification of active constituents with anti-epileptic and anti-psychotic activity from this plant may provide new directions for identification of active neuropharmacological agents, which could be given concomitantly during epilepsy and psychosis.... Это и многое другое вы найдете в книге Antiepileptic and antipsychotic activities of Oxalis corniculata Linn (Gaurav Gupta,Firoz Anwar and Muhammad Afzal)