STRUCTURE-ACTIVITY RELATIONSHIPS FOR PHARMACOTOXICOLOGICAL ENDPOINTS Iglika Lessigiarska, Andrew P. Worth and Mark T.D. Cronin (книга)

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Iglika Lessigiarska, Andrew P. Worth and Mark T.D. Cronin - «STRUCTURE-ACTIVITY RELATIONSHIPS FOR PHARMACOTOXICOLOGICAL ENDPOINTS»

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Quantitative structure-activity relationships (QSARs) are computer-based mathematical models that give information on the potential biological effects of compounds on the basis of their chemical structure alone. In this book, a research project on the development of QSARs for a range of toxicological endpoints, including cytotoxicity and acute toxicity, and biokinetic parameters related to the penetration of chemical compounds across the blood-brain barrier, is presented. Increasingly, legislation on the assessment and management of chemical risks, such as the REACH (Registration, Evaluation and Authorisation of Chemicals) Regulation in European Union, foresee an expanded use of QSARs as an alternative approach to (animal) testing of toxicity for the regulatory assessment of chemicals and chemical products. The research presented was performed at the Institute for Health & Consumer Protection (IHCP) of the European Commission''s Joint Research Centre (JRC) and at Liverpool John... Это и многое другое вы найдете в книге STRUCTURE-ACTIVITY RELATIONSHIPS FOR PHARMACOTOXICOLOGICAL ENDPOINTS (Iglika Lessigiarska,Andrew P. Worth and Mark T.D. Cronin)

Полное название книги Iglika Lessigiarska, Andrew P. Worth and Mark T.D. Cronin STRUCTURE-ACTIVITY RELATIONSHIPS FOR PHARMACOTOXICOLOGICAL ENDPOINTS
Тип Книга
Авторы Iglika Lessigiarska, Andrew P. Worth and Mark T.D. Cronin
Ключевые слова медицина, фармакология, медико-биологические дисциплины
Категории Образование и наука, Для техникумов и вузов
ISBN 9783838356808
Возрастное ограничение 18
Издательство
Год 2010
Название транслитом structure-activity-relationships-for-pharmacotoxicological-endpoints-iglika-lessigiarska-andrew-p-worth-and-mark-t-d-cronin
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