Excerpt from The Practitioner, Vol. 7
In a series of interesting lectures which M. Claude Bernard gave at the College de France, he examined with great care the anaesthetics, and chloroform in particular. I have no intention to review, here, the results obtained by M. Bernard; they will be found complete in various reports of his courses of lectures, especially in the Revue des Cours Scientifiques, for 1868 and 1869, and in the Gazette Hebdomadaire, 1869. There is a point, however, on which I desire to insist here, viz. the paralysing influence which the an?sthetised brain has, according to M. Bernard, on the other nervous centres; that is to say, on the spinal cord. My experiments, in fact, seem to me to contradict this view. The following is the fundamental experiment which led M. Bernard to the above-named conclusion: -
M. Bernard removed the circulation of a frog by taking away the heart and the viscera (the frog can, as is known, survive this mutilation for some hours); he then placed a ligature under the axill? so as to strangulate the integument en masse. Plunging, then, the anterior part of the animal into chloroform and water, or (more simply) injecting chloroform and water beneath the skin of the anterior portion of this frog, he an?sthctised not only the anterior portion beyond the ligature, but also the posterior limbs, which were the other side of the ligature. This result could not be obtained if the spinal cord had been previously divided.
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