Excerpt from The Canada Lancet and Practitioner
Members of the Toronto Academy of Medicine, Gentlemen: I regard the invitation to address you a great honor, and I hope that my acceptance may not be wholly without profit to you, and I can assure you that it is a great pleasure to me.
Much of my research work has been devoted to a study of the chemistry of bacteria. I have not succeeded in exhausting this field, and it is probable that I have falsely estimated even the meagre results which I have obtained, but I offer my contribution with the hope that it may induce others to enrich it. As my purpose in the start was to study the chemistry of bacterial cellular substance, my first task was to secure this material in large amounts, and fairly free from contamination. After many failures, I succeeded in doing this by means of my tanks for massive cultures, the construction and operation of which I will demonstrate by slides at the close of the hour. I have been able to obtain this material in satisfactory quantity and free from contamination.
It is generally assumed that bacteria are low forms of vegetable life. If cellulose be essential to vegetable cells, none of the bacteria which we have studied can be classed as vegetable organisms, since none contain cellulose. I would not classify bacteria among animal organisms, but would place them in a group by themselves. I have designated them as particulate proteins. We have found two carbohydrates in bacterial cellular substance. One is certainly a constituent of the nucleic acid group, while the other seems to be a chitin-like substance. Bacterial cells yield nucleic acid, and on disruption the xanthin bases are obtained.
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