Excerpt from First Principles of Medicine
The first step towards treating disease successfully, is to ascertain as far as possible, the nature of the alteration which has taken place in the seat of the disease, or what has been called technically the proximate cause; in default of this knowledge which is sometimes unattainable, we can only depend upon analogies, drawn from what we know to be the fact in other cases, and from physiology, which is a careful observation of the phenomena resulting from the functions of the different parts in health.
An accurate knowledge of the functions in their healthy state is the more necessary, because considerable deviations from the ordinary routine take place without disease, and as they are frequently much disturbed without any discoverable alteration in the structure of the organs having taken place, morbid anatomy alone will not be sufficient to elucidate all causes of disease, whilst on the other hand it is necessary to be aware that a considerably diseased change of structure may exist with little or no interruption of function.
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