Excerpt from The Edinburgh Medical Journal, Vol. 10
A considerable number of patients suffering from goitre have come under my care during the last fifteen years, and as their history and treatment is full of interest, I have thought it worth while to embody the results of my experience in a brief communication. Forty-two cases have been submitted to some form of operative procedure, and a smaller number have had medicinal and climatic treatment. The patients have come from the most varied localities. We will consider the latter class first. The medicinal treatment generally adopted has been the administration of iodide of potassium, with tincture of iodine, in the proportion of 3 grs. of the former with 1 minim of the latter. I have increased the dose of the tincture to 3 minims, but have never gone beyond this limit. The usual vehicle has been infusion of gentian, and the mixture has always been administered in a glass of water after meals. These large doses of iodine want careful watching, and should marked signs of iodism, or especially an?mia and weakness, supervene, the remedy must be discontinued. The thyroid extract, pushed to full doses, has also given good results in my hands, and I am quite unable at present to say what cases are benefited by iodine and what by thyroid extract. In one case only have I tried the hydriodic acid in the form of Gardner's syrup, and I found it answered well. The remedy is certainly worthy of a more extended trial. I have usually sent private patients to the East Coast, and I feel sure that sea air is a most important adjunct to the iodine treatment. I am aware that it is customary to minimise the influence of drugs upon this affection.
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