Intradermal Drug Delivery System is a noval approach for the formulation of pharmaceutical dosage forms to increase the bioavailability of drug with sustained action. IDDS for Trazodone-Hcl is really advantageous to treat patients with depression and schizophrenia. IDDS as Patch formulation is inserted in intradermal space to exert its effect. Biodegradable polymer used in its formulation help its biodegradtion under skin itself without any side effects so removal is not a big issue. Это и многое другое вы найдете в книге Formulation And Evaluation of IDDS For Depression; A NDDS (Suresh Jain)