Excerpt from Soaps and Proteins: Their Colloid Chemistry in Theory and Practice
The studies on soaps detailed in these pages were originally undertaken for the elucidation of various purely biological questions. The proof that widely differing theoretical and practical problems associated with the maintenance of normal physiology in plants and animals or in the treatment of their diseases are essentially problems in colloid-chemistry (more particularly problems in the colloid-chemistry of the proteins) made more an more evident the necessity for a better understanding of the nature of various colloid-chemical changes themselves. The chemistry of the proteins as chains of widely differing amino-acids presented, however, such an infinity of possible variables that every direct attempt to analyze their colloid-chemical behavior was beset with difficulty. For this reason we turned the soaps, for these substances not only contain a more controllable number of purely chemical variables, but their colloid-chemical behavior is much like that of the proteins. From the surer ground of the soaps it was then possible to step over into the more slippery one of the proteins. What are some of the bearings of our various conclusions upon the biological behavior of living cells under normal and abnormal circumstances is detailed in the pages that follow.
The reason why this volume is written as it is, is largely the fruit circumstance. While my first interests are biological and medical, it happens that generous friends have often asked me to present the work contained in this and some other of my books before their societies devoted to various branches of pure and applied chemistry. Due to such encouragement I have set down in this volume the substance of what was said to them and in which they saw relations to their own field of endeavor.
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